Present post:

Years of service: From 1989 to date
Title: Assistant Professor
Name and full address of the Institution
Disciplines of Clinical Pathology, Medical Informatics and Telemedicine
Department of Pathology, School of Medicine of The University of São Paulo
Avenida Doutor Arnaldo 455, São Paulo, SP, CEP 01246-903, BRAZIL
Tel: +55 11 3066 7435 Fax: +55 11 881 7717

Summary of Research Activities

Since 1987 working with both serology and mathematical modelling applied to the development of vaccination strategies, based on data obtained by populational serosurveys and seroconversion studies for rubella, measles, hepatitis A, varicella, rotavirus A, cytomegalovirus, RSV, HIV, hepatitis C and hepatitis B, in collaboration with Prof.Dr. Eduardo Massad.

The results of the vaccination strategy design against rubella of his PhD thesis were applied by the Health State Secretary of São Paulo in 1992, when the immunisation programme against this infection was introduced for the first time in a State of Brazil.

Post-doctoral fellowship with Prof. Roy Anderson and Dr. James Nokes in 1993, at Imperial College of Science, Technology and Medicine, University of London, England, UK. During the year of 1993, he spent also 3 months at the Public Health Laboratory Service, London, UK, with Dr. Bernard J. Cohen and Dr. David W.G. Brown, Division of Virology, where it was developed the technique for antibody detection against rubella in saliva samples.

Current activities include the coordination of the PhD Programme of Pathology, at the School of Medicine of The University of São Paulo, and the supervision of PhD students developing their work on:

1. Vaccination strategies against infectious diseases;
2. HIV transmission, pathology and seroepidemiology;
3. Testing of new therapeutic methods
4. Medical education and evaluation

List of most relevant publications

1. MM Yuki, HP Martins, LN Castilho, RS de Azevedo Neto. Avaliação crítica da interferência na dosagem de creatinina sérica pela reação de Jaffé. Revista da Sociedade Brasileira de Patologia Clínica, 25:47-51 (1989)
    
2. AJ Vaz, EM Guerra, LCC Ferratto, LAS Toledo, RS Azevedo Neto. Sorologia positiva para sífilis, toxoplasmose e Doença de Chagas em gestantes de primeira consulta em Centros de Saúde de área metropolitana, Brasil. Revista de Saúde Pública, 24:373-379 (1990)
    
3. MAG Munhoz, EY Gushiken, NR Pacheco, SB Campa, C Kitamura, RS de Azevedo Neto. Uso de amostra controle na avaliação da reprodutibilidade de equipamentos semi-automatizados em hematologia laboratorial: uma proposta de controle de qualidade para laboratórios de saúde pública. Revista do Instituto Adolfo Lutz, 51:41-45 (1991)
    
4. CCM Santos, IK Yokomizo, C Kitamura, RM Yokomizo, RS de Azevedo Neto. Performance e características de soro controle pronto para uso. LAES, 75:43-48 (1992)
    
5. FAB Coutinho, E Massad, MN Burattini, HM Yang, RS Azevedo Neto. Effects of vaccination programmes on transmission rates of infections and related threshold conditions for control. IMA Journal of Mathematics Applied in Medicine & Biology, 10:187-206 (1993)
    
6. MAG Munhoz, RM Yokomizo, EY Gushiken, VMC Zamfirov, IC Arruda, FA Cangerana, LI Niero, RS de Azevedo Neto. Determinação de valores-alvo para uso no controle de qualidade de analisadores hematológicos. Revista do Instituto Adolfo Lutz, 53:41-47 (1993)
    
7. E Massad, MN Burattini, RS Azevedo Neto, HM Yang, FAB Coutinho, DMT Zanetta. A model-based design of a vaccination strategy against rubella in a non-immunized community of São Paulo State, Brazil. Epidemiology and Infection, 112:579-594 (1994)
    
8. RS Azevedo Neto, ASB Silveira, DJ Nokes, HM Yang, SD Passos, MRD Cardoso, E Massad. Rubella seroepidemiology in a non-immunized population of São Paulo State, Brazil. Epidemiology and Infection, 113:161-173 (1994)
    
9. RS Azevedo Neto, A Richards, DJ Nokes, ASB Silveira, BJ Cohen, SD Passos, VAUF Souza, DWG Brown, CS Pannuti, E Massad. Salivary antibody detection in epidemiological surveys: a pilot study after a mass vaccination campaign against rubella in São Paulo, Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene, 89:115-118 (1995)
    
10. Massad, E; Azevedo Neto, RS; Yang, HM; Burattini, MN; Coutinho, FAB Modelling age-dependent transmission rates for childhood infections. Journal of Biological Systems, 3(3):803-812 (1995)
     
11. E Massad, RS Azevedo Neto, MN Burattini, DMT Zanetta, FAB Coutinho, HM Yang, JC Moraes, CS Pannuti, VAUF Souza, ASB Silveira, CJ Struchiner, GW Oselka, MCC Camargo, TM Omoto, SD Passos. Assessing the efficacy of a vaccination strategy against rubella in São Paulo, Brazil. International Journal of Epidemiology, 24(4):842-850 (1995)
     
12. Struchiner, CS; Brunet, R; Halloran, ME; Massad, E and Azevedo Neto, RS. On the use of State-space models for the evaluation of health interventions. Journal of Biological Systems, 3(3):851-865 (1995)
     
13. Silveira, PSP; Yang, HM; Azevedo-Neto, RS and Massad, E. Mathematical and computer models for infective contact rates. Mathematical Modeling and Scientific Computing , 6:793-798 (1996)
     
14. Yang, HM; Yamamoto, JF; Azevedo-Neto, RS; Silveira, ASB and Massad, E. The use of quasi-periodic phenomenon in epidemics to design a pulse vaccination campaign. Mathematical Modeling and Scientific Computing, 6:799-804 (1996)
     
15. Massad, E; Struchiner, CJ; Azevedo-Neto, RS; Halloran, ME and Brunet, RC. Modeling the impact of heterogeneities in individual frailty on epidemic. Mathematical Modeling and Scientific Computing, 6:816-821 (1996)
     
16. Yee, CJ; Morato-Castro, FF; Palma, MS; Malaspina, O; Azevedo Neto, RS; Costa-Manso, E; Croce, J Acquired immunity to Africanized honeybee (Apis mellifera) venom in Brazilian beekeepers. Journal of Investigation Allergology and Clinical Immunology, 7(6):583-587 (1997)
     
17. Cox MJ, James VLA, Azevedo RS, Massad E, Medley GF. Infection with group C rotavirus in a suburban community in Brazil. Tropical Medicine & International Health, 3 (11):891-895(1998)
     
18. Halloran, ME; Anderson, RM; Azevedo-Neto, RS; Bellini, WJ; Branch, O; Burke, MA; Compans, R; Day, K; Gooding, L; Gupta, S; Katz, J; Kew, O; Keyserling, H; Krause, R; Lal, AA; Massad, E; McLean, AR; Rosa, P; Rota, P; Wiener, P; Wynn, SG; Zanetta, DMT Population biology, evolution, and immunology of vaccination and vaccination programs. The American Journal of the Medical Sciences, 315(2):76-86 (1998)
     
19. Cox, MJ; Azevedo, RS; Nokes, DJ; Beards, GM; McCrae, MA; Massad, E; Medley, GF Seroepidemiology of Group A rotavirus in suburban São Paulo, Brazil. Epidemiology and Infection, 120:327-334 (1998)
     
20. LM de Almeida, MCE da Costa, RR Luiz, PE Coletty, RS de Azevedo, VA Machado, CM Coeli, E Massad. Soroprevalência da Hepatite A no município de Duque de Caxias, Rio de Janeiro, Brasil. Cadernos de Saúde Coletiva, 6(S1):39-48 (1998)
     
21. Burattini, MN; Massad, E; Coutinho, FAB; Azevedo-Neto, RS; Menezes, RX; Lopez, LF A mathematical model of the impact of crack-cocaine use on the prevalence of HIV/AIDS among drug users. Mathematical Computing and Modelling, 28(3):21-29 (1998)
     
22. Cox MJ; Azevedo RS; Cane PA; Massad E; Medley GF. Seroepidemiological study of Respiratory Syncytial Virus in São Paulo State, Brazil. Journal of Medical Virology, 55(3):234-239 (1998)
     
23. Rozman, M; Massad, E; Silveira, ASB; Azevedo-Neto, RS; Takey, K; Yamamoto; YI; Strazza, L; Carvalho, HB; Buchalla, CM; Schestman, M & Burattini, MN. HIV/AIDS in a Brazilian prision. International Journal of STD & AIDS, 9(3):183-184 (1998)
     
24. Cox, MJ; Azevedo, RS; Massad E; Fooks, AR; Nokes, DJ. Measles antibody levels in a vaccinated population in Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene, 92:227-230 (1998)
     
25. Massad E, Rozman M, Azevedo RS, Silveira ASB, Takey K, Yamamoto YI, Strazza L, Ferreira MMC, Carvalho HB, Burattini MN. Seroprevalence of HIV, HCV and syphilis in Brazilian prisoners: Preponderance of parenteral transmission. European Journal of Epidemiology, 15(5):439-445 (1999)
     
26. Struchiner CJ, de Almeida LM, de Azevedo RS, Massad E. Hepatitis A incidence rate estimates from a pilot seroprevalence survey in Rio de Janeiro, Brazil. International Journal of Epidemiology, 28(4):776-781 (1999)
     
27. Coutinho FAB, Massad E, Lopez LF, Burattini MN, Struchiner CJ, Azevedo-Neto RS. Modelling heterogeneities in individual frailties in epidemic models. Mathematical and Computer Modelling, 30(1-2):97-115 (1999)
     
28. LM Almeida, RS Azevedo, AAM Guimarães, ESF Coutinho, CJ Struchiner, E Massad. Detection of antibodies against hepatitis A virus in eluates of blood spotted on filter-paper: a pilot study in Rio de Janeiro, Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene, 93:401-404 (1999)
     
29. VA dos Santos, RS Azevedo, ME Camargo, VAF Alves. Serodiagnosis of hepatitis C virus - Effect of new evaluation of cutoff values for enzyme-linked immunosorbent assay in Brazilian patients. American Journal of Clinical Pathology, 112(3):418-424 (1999)
     
30. Zanetta DMT, Strazza L, Azevedo RS, Carvalho HB, Massad E, Menezes RX, Ferreira DP, Burattini MN. HIV infection and related risk behaviours in a disadvantaged youth institution of São Paulo, Brazil. International Journal of STD & AIDS, 10(2):98-104 (1999)